Masui. The Japanese journal of anesthesiology
-
Randomized Controlled Trial Clinical Trial
[Comparison of propofol and pentazocine combined with thiamylal for laryngeal mask insertion].
We evaluated the combination of pentazocine and thiamylal as induction agents for laryngeal mask airway (LMA) insertion and compared this with propofol. Ninety-four patients, ASA grade 1 or 2, were randomly assigned to one of four induction groups as follows; group P: propofol 2.5 mg.kg-1, group p 0.3: pentazocine 0.3 mg.kg-1 followed by thiamylal 5 mg.kg-1, group p 0.6: pentazocine 0.6 mg.kg-1 followed by thiamylal 5 mg.kg-1, and group T: thiamylal 5 mg.kg-1. In group T (n = 5), insertion of LMA was impossible due to inadequate anesthesia. ⋯ Heart rate did not show any significant change. We conclude that the induction with the combination of pentazocine and thiamylal provides suitable conditions for LMA insertion with more stable hemodynamics compared with propofol. Doses of 0.3 mg.kg-1 seem to be desirable for LMA insertion.
-
Randomized Controlled Trial Clinical Trial
[Anesthesia induction for laryngeal mask insertion--comparison among sevoflurane, isoflurane and propofol].
We compared the patient's response to laryngeal mask (LM) insertion and hemodynamics among three anesthesia induction methods; S group used sevoflurane and slowly increased to 5% in 50% nitrous oxide; I group used isoflurane and slowly increased to 3% in 50% nitrous oxide; and P group used 2.5 mg.kg-1 propofol with 0.2 microgram.kg-1 fentanyl. Thirty patients, 35 to 65 years, for elective mastectomy were the subjects of study in each of the three groups. Preanesthetic medication was composed of i.m. injection of 0.5 mg atropine and 5 mg midazolam 30 min. prior to the induction. ⋯ Blood pressure (BP), heart rate (HR) and rate pressure product (RPP) in the P group were significantly lower than those in the other two groups. I group showed significant increase in BP, HR and RPP. It was concluded that sevoflurane enabled the most smooth insertion of LM among the three methods of anesthesia with the least hemodynamic change.