Masui. The Japanese journal of anesthesiology
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Randomized Controlled Trial Comparative Study Clinical Trial
[Comparison of 8 mg and 10 mg hyperbaric bupivacaine during spinal anesthesia for cesarean section in Japanese parturients].
Hypotension after spinal anesthesia for cesarean section is common and may result in serious complications despite the use of uterine displacement and volume preloading. Adequate amount of hyperbaric bupivacaine for Japanese parturients whose frames are generally smaller than those of Caucasian counterparts have not yet been examined. We compared the analgesic efficacy and the incidence of hypotension with 8 mg versus 10 mg hyperbaric bupivacaine during spinal anesthesia for cesarean section in Japanese parturients. ⋯ Injection of 8 mg hyperbaric bupivacaine is preferable than 10 mg in spinal anesthesia for cesarean section to obtain adequate analgesic efficacy and to avoid maternal hypotension.
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Randomized Controlled Trial Clinical Trial
[Effects of olprinone hydrochloride after coronary artery bypass grafting].
We have examined the effect of olprinone hydrochloride on hemodynamics and peripheral circulation after cardiopulmonary bypass (CPB) in 56 patients who underwent coronary artery bypass grfting. ⋯ Olprinone increased CI and decreased SVRI, and it led to easy weaning from CPB, providing excellent hemodynamics after CABG. These results suggest that olprinone hydrochloride 15 micrograms.kg-1 bolus plus 0.1 microgram.kg-1.min-1 continuous administration may be effective for improvement of hemodynamics and peripheral circulation after CPB.