Masui. The Japanese journal of anesthesiology
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Randomized Controlled Trial
[Neuromuscular blocking effects, pharmacokinetics and safety of Org 9426 (rocuronium bromide) in Japanese patients].
The purpose of this study was to examine pharmacodynamics, pharmacokinetics and safety of Org 9426 (rocuronium bromide) in Japanese patients. ⋯ The efficacy of neuromuscular block, stable pharmacokinetic behavior and excellent safety of Org 9426 were also confirmed in Japanese surgical patients.
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Pentazocine is one of the most popular analgesics for postoperative analgesia in Japan. For patient-controlled analgesia (PCA), however, opioid agonists are used commonly, and little information is available concerning PCA by pentazocine. We studied the effects of postoperative PCA using intravenous pentazocine. ⋯ Our program of PCA was safe and effective for postoperative analgesia. But the guidance for patients, surgeons and nursing staff is important using PCA therapy more effectively.
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Epiglottic cysts often cause difficulty in airway management. A 71-year-old man had extraction for an epiglottic cyst of 4 cm in diameter. Anesthesia was induced with small divided doses of propofol. ⋯ The operation was finished in 55-min and the patient was extubated 15 min after the end of the operation. His postoperative course was uneventful and he was discharged from the hospital three days after the operation. The authors conclude that the combined use of the laryngoscope and Trachlight is helpful for endotracheal intubation in patients with large epiglottic cysts.
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We report a case of general anesthesia for laparoscopic cholecystectomy at 12 weeks of gestation. A 20-year-old woman weighing 123 kg was admitted with epigastralgia. ⋯ Laparoscopic cholecystectomy was performed uneventfully under general anesthesia combined with epidural anesthesia. There were no clinical signs of fetal distress during the perioperative period.