Masui. The Japanese journal of anesthesiology
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We report a case of late-onset systemic toxicity due to ropivacaine over dose, and its successful reversal with 20% lipid emulsion (20% Intralipos). A 40-year-old woman, 40 kg, ASA-I, was scheduled for laparoscopy-assisted myomectomy of the uterus in which 40 ml of 0.375% ropivacaine was injected for bilateral US guided transversus abdominis plane block (TAPblock) under general anesthesia. Anesthesia proceeded uneventfully and she could go back to the ward 15 min later, but 3 hours after TAPblock, her blood pressure dropped to seventies and she became unresponsive. ⋯ She received a total of 230 ml 20% Intralipos, which was discontinued due to her rapid emergence with no further seizure episodes. This case suggests that early and sufficient use of lipid emulsion may lead to a good outcome. We recommend the immediate availability of lipid emulsion along with other emergency therapeutics at the ward after TAPblock.
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A 12-year-old girl with severe scoliosis underwent an operative procedure for correction of her spine deformity. Spinal cord injury is one of the most feared complications of scoliosis surgery. ⋯ We used an intraoperative wake-up test with the concept of target-controlled infusion and total intravenous anesthesia (propofol and remifentanil). The use of Bispectral Index monitoring as a measure of depth of anesthesia enabled the patient to awake rapidly and consequently we did an immediate evaluation of muscle strength of lower extremities.
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To prevent peripheral nerve injury and neuropathic pain resulting from venipuncture, medical students and medical workers should be educated about the following points in clinical practice. First, the medial aspect of the antecubital fossa should not be punctured, to prevent injury to the median and medial anterobrachial cutaneous nerves. Second, the symptoms and signs of neuropathic pain resulting from venipuncture should be taught, to recognize the onset of neuropathic pain. Third, pharmacotherapy for the management of neuropathic pain should be taught to treat neuropathic pain resulting from venipuncture.