Acta anaesthesiologica Belgica
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Acta Anaesthesiol Belg · Jan 2010
Randomized Controlled TrialGabapentin premedication: assessment of preoperative anxiolysis and postoperative patient satisfaction.
Gabapentin reduces anxiety in psychiatric patients. In this prospective, randomized, double-blinded, placebo-controlled study, we investigated whether a single dose of gabapentin as a premedicant reduces preoperative anxiety, and improves patient satisfaction. ⋯ A single dose of gabapentin has proven to be an effective premedication to reduce preoperative anxiety.
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Acta Anaesthesiol Belg · Jan 2010
Randomized Controlled TrialEffect of the addition of rocuronium to local anesthetics for peribulbar block.
To test the hypothesis that rocuronium added to a mixture of local anaesthetics could improve akinesia in Peribulbar Block (PB) we designed this prospective, randomized, double-blinded study. Sixty ASA physical status I and II patients presenting for cataract surgery (manual extracapsular lens extraction) under PB were included. Patients were randomized to 2 groups: rocuronium group (n = 30) received PB with a local anesthetic mixture (Lidocaine 2% + Bupivacaine 0.5%) to which was added 0.06 mg/Kg of rocuronium and control group (n = 30) received PB with the same mixture to which was added saline. ⋯ Supplementary injection was necessary in 4 patients (13%) in rocuronium group versus 12 patients (40%) in control group (p = 0.039). No significant complications were recorded. Rocuronium added to a mixture of local anaesthetics at a dose of 0.06 mg/Kg improved the quality of akinesia in PB and reduced the need for supplementary injections.