Anestezjologia intensywna terapia
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Anestezjol Intens Ter · Jan 2011
Randomized Controlled Trial[Effect of pre-emptive pregabalin on pain intensity and morphine requirement after hysterectomy].
Pregabalin, an antiepileptic and chronic pain medication, has been used by various authors for preoperative analgesia. We have assessed the effect of pre-emptive administration of the drug to patients scheduled for elective abdominal hysterectomy. ⋯ We conclude that pre-emptive administration of 300 mg pregabalin reduces postoperative pain and morphine consumption. Further studies on higher doses would appear to be justified.
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Anestezjol Intens Ter · Jan 2011
Randomized Controlled Trial[Pre-emptive ketoprofen for postoperative pain relief after urologic surgery].
Effective multimodal postoperative analgesia is one of determinants of patient satisfaction after successful surgery. Following the recommendations of non-steroidal antiinflammatory agents (NSAIDs) for pre-emptive analgesia, we assessed the efficacy of ketoprofen administered before urological surgery. ⋯ Pre-emptive analgesia with intravenous ketoprofen was ineffective in patients undergoing urological surgery.
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Anestezjol Intens Ter · Jan 2011
Randomized Controlled Trial[Comparison of atracurium, cisatracurium and vecuronium during anaesthesia for laparoscopic surgery].
The aim of the study was to compare the intubating conditions, onset time, and duration of action of atracurium, cisatracurium, and vecuronium, when used for muscle relaxation in laparoscopic surgery with carbon dioxide inflation. In trying to find an "ideal" relaxant we compared the relative potency of these drugs, and also measured pH, PaCO2 and skin temperature. ⋯ Vecuronium, besides providing excellent conditions for tracheal intubation, had the fastest onset time and optimal duration of action. We found the drug to be the most suitable for laparoscopic surgery.