Revista española de anestesiología y reanimación
-
Rev Esp Anestesiol Reanim · May 1992
Randomized Controlled Trial Clinical Trial[Changes in plasma cortisol and ACTH caused by diazepam, bromazepam, triazolam, and alprazolam in oral premedication].
Benzodiazepines relieve anxiety and modify the endocrine response to surgical-anesthetic stress. ⋯ Benzodiazepines failed to modify cortisol and ACTH levels during surgery and during the immediate postoperative period. The most marked attenuation of adrenocortical response was achieved with 12 mg of bromazepam and the less marked lessening was induced by 0.5 mg of alprazolam.