Revista española de anestesiología y reanimación
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Rev Esp Anestesiol Reanim · May 1995
Randomized Controlled Trial Comparative Study Clinical Trial[Intravenous anesthesia using propofol during lengthy neurosurgical interventions].
To compare the hemodynamic stability and time to recovery of consciousness after long-duration (> 3 h) neurosurgery with 2 anesthetic protocols: total intravenous anesthesia with propofol as the single hypnotic agent and inhalational anesthesia with isoflurane. ⋯ Propofol can be considered an alternative to the traditional thiopental-isoflurane sequence in neurosurgery lasting more than 3 h. In our study the hypertensive response to the stimulus of orotracheal intubation was lower in the propofol group than in the thiopental-isoflurane group.