Revista española de anestesiología y reanimación
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Rev Esp Anestesiol Reanim · Jun 2002
Multicenter Study[Prospective epidemiologic study of perioperative anaphylactoid reactions occurring in Catalonia (1996-7)].
To determine the incidence, immunological mechanisms, severity and clinical course of perioperative allergic reactions. ⋯ The frequency of allergic reactions in Catalonia is 1 case per 10,263 anesthesias performed, but the rate is higher in general anesthesia. Fifty-six percent of the reactions were severe. Most developed immediately and the moment of induction involved the greatest risk. Early assessment of methylhistamine and tryptase levels has been shown to be useful and positivity is linearly associated with severity of reaction. In 62.5% of the patients, positive results were seen in skin tests performed later.