Revista española de anestesiología y reanimación
-
Rev Esp Anestesiol Reanim · Jan 2012
Review Meta Analysis[Levosimendan reduces mortality in cardiac surgery: a systematic review and meta-analysis].
To evaluate whether Levosimendan has any impact on peri-operative mortality in cardiac surgery. ⋯ The meta-analysis showed that the use of Levosimendan was associated with a reduction in mortality in patients subjected to cardiac surgery, although there is still no definitively clear evidence. Additional randomised and multicentre clinical studies, with a much larger number of patients are required, in which hospital mortality and mortality at 6 months are analysed as the primary outcomes.