Journal of the Medical Association of Thailand = Chotmaihet thangphaet
-
Randomized Controlled Trial
Application of mometasone spray to reduce sore throat after tracheal intubation.
Many factors in tracheal intubation lead to postoperative sore throat from mucosal injury. Mometasone furoate spray is a moderate potency corticosteroid that prevents influx of inflammatory cells into the mucosa. The present study assessed the efficacy of this drug for reducing postoperative sore throat. ⋯ Application of mometasone spray reduces postoperative sore throat after tracheal intubation.
-
Randomized Controlled Trial
Predicted EC50 of propofol using target controlled infusion with and without fentanyl for colonoscopy.
To determine the propofol effect site target concentration at which 50% of patients did not respond to stimulation for colonoscopy (EC50colonoscopy) using a target controlled infusion (Schnider model) and to investigate whether fentanyl reduces these required concentrations. ⋯ The propofol EC50 for colonoscopy was decreased by supplemental 1 mcg/kg fentanyl with no significant difference in hemodynamic values between the two groups.
-
Randomized Controlled Trial
Alcohol-based chlorhexidine vs. povidone iodine in reducing skin colonization prior to regional anesthesia procedures.
Povidone-iodine is a commonly used antiseptic for preparing the skin for regional anesthesia. However chlorhexidine solution has been demonstrated superior for skin preparation before insertion of intravascular devices, taking of blood cultures and before epidural insertion in children. The information regarding the initial efficacy of these disinfectants has not yet been defined The purpose of the present study was to investigate the initial efficacy ofan alcohol-based chlorhexidine and povidone iodine solution as the antiseptic of choice for all regional techniques. ⋯ For skin disinfection prior to the neuraxial blockade procedure, the use of alcohol-based chlorhexidine compared with the use of povidone iodine lowered the incidence of insertion-site-colonization.
-
Randomized Controlled Trial
A comparison of spinal isobaric levobupivacaine and racemic bupivacaine for lower abdominal and lower extremity surgery.
Levobupivacaine is a new long-acting local anesthetic, which is the isolated S-enantiomer of racemic bupivacaine with less cardiovascular and central nervous system toxicity than bupivacaine. Reports using levobupivacaine for epidural or brachial plexus anesthesia suggested equivalent clinical efficacy to bupivacaine. However, inadequate information for spinal anesthesia was found ⋯ The present study indicated that 15 mg of isobaric racemic bupivacaine and levobupivacaine for spinal anesthesia had equivalent peak block height and showed equally effective efficacy regarding to both the onset time and duration of motor and sensory blockade.
-
Randomized Controlled Trial
Prevalence of pin-site infection: the comparison between silver sulfadiazine and dry dressing among open tibial fracture patients.
Pin-site infection is one of the most troublesome complications of external fixation. The present study aimed to compare the rate of pin-site infection following silver sulfadiazine with dry dressing. ⋯ There was no significant difference in prevalence of pin-site infection between both groups (p = 0.97). Therefore, either silver sulfadiazine or dry dressing could be advocated.