Journal of opioid management
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Randomized Controlled Trial Comparative Study
Bioequivalence and safety of a novel fentanyl transdermal matrix system compared with a transdermal reservoir system.
Fentanyl is a potent synthetic opioid used for the management of chronic pain. A newer transdermal matrix system was developed and compared with a reservoir system used in the United States. ⋯ The transdermal fentanyl matrix system adhered well, was well tolerated, and produced systemic exposures of fentanyl that were bioequivalent to the reservoir system.