The American review of respiratory disease
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Am. Rev. Respir. Dis. · Jan 1983
Small airways in severe panlobular emphysema: mural thickening and premature closure.
Histological measurements in cases of severe paniobular and centrilobular emphysema and in normal lungs disclosed a generalized thickening of the walls of small airways in the panlobular group. With mathematical models, this was depicted as a potential basis for airway closure at higher than normal lung volumes and trapping of air. ⋯ Bronchiolar thickening is one such general process. Present findings suggest that this is prone to be linked to emphysema with a panlobular pattern.