Danish medical journal
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Danish medical journal · Apr 2020
Initial experiences from patients with COVID-19 on ventilatory support in Denmark.
The coronavirus disease 2019 (COVID-19)pandemic reached Denmark in early 2020. This paper presents initial intensive-care unit (ICU) experiences with COVID-19 patients at Roskilde Hospital, which was the primary recipient of COVID-19 patients in need of intensive care in the Zealand Region, Denmark. ⋯ none.
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Danish medical journal · Jul 2019
Multicenter Study Observational StudyTemporal trends in length of stay and readmissions after fast-track hip and knee arthroplasty.
Implementation of fast-track protocols in total hip and knee arthroplasty (THA/TKA) has dramatically changed the perioperative care, leading to a subsequent reduction in post-operative length of stay (LOS) and mor-bidity. Previous investigations in Denmark have shown a reduction in LOS from about ten days in 2000 to four days in 2009. We aimed to describe temporal changes in LOS and readmissions within the context of a continuous multicentre collaboration focusing on enhancing recovery and reducing morbidity after fast-track THA and TKA. ⋯ The study was supported by an unconditional PhD grant from Lundbeckfonden to PBP (R230-2017-166).
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Danish medical journal · Jan 2019
A nationwide cohort study of short- and long-term outcomes following emergency laparotomy.
Emergency laparotomy is a high-risk procedure associated with severe post-operative morbidity and high mortality. The aim was to conduct a nationwide cohort consisting of all patients undergoing emergency laparotomy during an 11-year period and to examine both short- and long-term outcomes. ⋯ This study received support from the Frimodt-Heinecke Foundation and from the foundation Manufacturer Frands Køhler Nielsens and wife memorial fund.
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Iron deficiency and anaemia in the puerperium are associated with several important clinical consequences, most prominently physical fatigue. Current treatment practice with oral iron supplementation is associated with gastrointestinal side-effects and subsequent poor compliance. Red blood cell transfusion is also widely used to treat severe postpartum anaemia, though accumulating evidence questions its risk-benefit ratio. ⋯ The difference in biochemical markers was larger than the patient-reported outcomes in the first week. A larger trial is needed to determine whether a high single-dose iron infusion is non-inferior to red blood cell transfusion in severe postpartum anaemia. The third study compared iron concentration in breast milk in a randomised sample of women receiving high single-dose iron infusion or oral iron. A high single-dose iron infusion lead to a transient increase in the iron concentration in breast milk, which remained within the normal range. In conclusion, iron isomaltoside seems to be associated with improved patient-reported outcomes compared to oral iron treatment, and in severe postpartum anaemia intravenous iron seems promising as an alternative to red blood cell transfusion.