Anesteziologiia i reanimatologiia
-
Anesteziol Reanimatol · Jul 2011
Randomized Controlled Trial[Using of tranexamic acid (Tranexam) for prevention and correction of coagulopathy during brain tumors removal].
The aim of the study is to estimate clinical effectiveness of fibrinolysis inhibitor Tranexam in neurosurgical patients with intracranial tumors. The medication was prescribed to 78 patients from 27 to 65 years old. The control group consisted of 57 patients. ⋯ Drainage blood loss was lower in the main group (267 +/- 23 ml a day) than in the control group (340 +/- 28 ml a day). Medication injection during diffuse bleeding from small vessels led to quick and visible bleeding reduction. Thus Tranexam decreases the risk of intraoperative blood loss in the patients with brain tumors.