Anesteziologiia i reanimatologiia
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Anesteziol Reanimatol · Jan 2015
Randomized Controlled Trial[Comparison of sedation with dexmedetomidine and haloperidol in patients with delirium after femoral neck fractures].
Delirium seriously complicates the recovery period after surgery, injury and increases mortality in elderly patients with femoral fractures. ⋯ We examined 80 geriatric patients admitted to the Institute of Traumatology and Orthopedics in Astana in the period from September 2012 to June 2014. We evaluated the efficacy of dexmedetomidine and haloperidol sedation according to RASS, communication ability and level of tolerance of procedures. The effect of dexmedetomidine was better and was expressed 30.3% decreasing of the duration of delirium in comparison with haloperidol (p < 0.05). Overall assessment of the ability of patients to the interaction, cooperation and tolerance of procedures evaluated by nurses, was higher in the dexmedetomidine group compared with haloperidol, as well as evaluating the effectiveness of individual communication and cooperation (8.3 ± 2.3 points vs 4.5 ± 1.9 points, p < 0.05). Despite the development of bradycardia in a small number of patients, as well as headaches and nausea after stopping the infusion, dexmedetomidine provided a more controlled and safe sedation compared with haloperidol.
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Anesteziol Reanimatol · Jan 2015
Randomized Controlled Trial[Effect of succinate-containing solution on the level of metabolism during perioperative period in children].
A randomized prospective study. ⋯ Reamberin 1.5% promotes to increase the level of basal metabolism in the early postoperative period, decreases the duration of awakening periods, improves recovery of motor activity and adequate breathing.
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Anesteziol Reanimatol · Jan 2015
Randomized Controlled Trial[Influence of remote ischemic preconditioning on brain injury markers dynamics during cardiopulmonary bypass].
Remote ischemic preconditioning has gained clinicians' attention as a technique to protect the heart in patients undergoing cardiac surgery under cardiopulmonary bypass. While experimental data report neuroprotective properties of remote ischemic preconditioning, we failed to find any clinical studies investigating its effects on neurologic outcome in cardiac surgery. ⋯ Our data suggest that remote ischemic preconditioning does not affect neuronal damage and neurologic outcome in patients operated under cardiopulmonary bypass.