Anesteziologiia i reanimatologiia
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Anesteziol Reanimatol · Nov 2010
Randomized Controlled Trial[Concentration of 8-isoprostaglandin F2alpha depending on type of anesthesia in laparoscopic surgery in gynecology].
The article represents a randomized comparative study including 100 patients from 21 to 34 years old who has underwent a laparoscopic surgery in V. I. ⋯ Assessment of the serum 8-isoprostaglandin F2alpha before the surgery and 2 hours after the end of surgery has shown the increase of this oxidative stress marker in the early post-surgery period. However, in spinal anaesthesia group, the increase was significantly lower, indicating a more physiological nature of this method of anaesthesia.
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Anesteziol Reanimatol · May 2010
Randomized Controlled Trial[Difficult tracheal intubation: comparative assessment of the value of prognostic indices in using Macintosh and Truview laryngoscopes].
The paper describes the experience in using three predictive criteria, such as Mallampati test, Patila test, and ULBT test, to evaluate tracheal intubation and compares their predictive validity. The experience in applying Macintosh and Truview laryngoscopes to patients with predicted difficult tracheal intubation (DTI) is also depicted. ⋯ No significant correlation was obtained between the other criteria of DTI and the difficulties during intubation at the first attempt (p > 0.05). There was no statistical significant correlation between the used type of a laryngoscope and the rate of effective/ineffective intubations at the first attempt (r = 0.34; p > 0.05).
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Anesteziol Reanimatol · Sep 2009
Randomized Controlled Trial Multicenter Study Comparative Study[Evaluation of the effectiveness and safety of synthetic colloid solutions in the treatment of severe abdominal sepsis: a randomized comparative study].
Infusion therapy, surgical debridement of an infection focus, and antimicrobial therapy are basic treatments for severe sepsis. At the same time there are no uniform guidelines on how to choose fluids for infusion therapy. ⋯ The presented multicenter, randomized comparative study has evaluated different synthetic colloid solutions in early targeted therapy for severe sepsis. Evidence is provided for the identical effectiveness of the compared solutions in correcting hypovolemia and stabilizing hemodynamics in patients with severe sepsis and septic shock.
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Anesteziol Reanimatol · Sep 2009
Randomized Controlled Trial Multicenter Study[Correction of intracranial hypertension syndrome using hyperosmolar solutions in patients with severe brain damage (multicenter randomized clinical study)].
The paper presents the results of a muticenter study of the effect of 3 hyperosmolar solutions (15% mannitol solution, 10% sodium chloride solution, and the combined solution HyperHAES containing 7.2% sodium chloride and hydroxyethyl starch 200/0.5) on the value of intracranial pressure (ICP) (invasive ICP monitoring) and systemic hemodynamic parameters (PiCCOplus) in 94 clinical cases of intracranial hypertension (ICP more than 20 mm Hg) in 25 patients with acute cerebral pathology (severe brain injury, aneurysmatic subarachnoid hemorrhage). Intravenous infusion of the solutions was found to induce a reduction in ICP; however, this was most pronounced (by 30-40%) and longer (up to 4 hours) when HyperHAES solution was used. This solution produced not only an osmotic, but also hemodynamic effect.
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Anesteziol Reanimatol · Sep 2009
Randomized Controlled Trial[Target-oriented infusion therapy in patients during myocardial revascularization].
The paper analyzes goal-oriented infusion therapy used during myocardial revascularization on the working heart. Forty-seven patients with coronary heart disease were examined. Group 1 (control) (n = 20) received standard infusion therapy (a combination of colloids and crystalloids (1:1) at a rate of 6-7 ml/kg/h, by being oriented to indices, such as heart rate, blood pressure, central venous pressure, and diuresis rate. ⋯ In this group, a volume load was done at the beginning of an operation until the maximum possible SV resulted from increased preload (global end-diastolic volume index). The goal of infusion therapy throughout the operation was to maintain these values of the latter index. Goal-oriented infusion therapy, the purpose of which was to determine and maintain the individual optimal values of preload, was found to minimize hemodynamic disorders at surgery and to reduce the frequency of use of cardiotonic agents and the duration of artificial ventilation.