Anesteziologiia i reanimatologiia
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Anesteziol Reanimatol · Mar 2007
Randomized Controlled Trial[Procedures for preventing postoperative nausea and vomiting after laparoscopic cholecystectomy: dexamethasone and ondansetron].
This randomized double-blind study was undertaken to evaluate the efficacy of ondasetron and dexamathesone in reducing the incidence of postoperative nausea and vomiting after laparoscopic cholecystectomy. The study covered 60 patients (ASA I/II) who had undergone laparoscopic cholecystectomy under general anesthesia. The patients were divided into two groups: 1) 30 patients who received dexamethasone, 4 mg i.v.; and 2) 30 patients who took ondansetron, 4 mg i.v., prior to general anesthesia. ⋯ The least intensity of postoperative pain was observed in Group 1, but the difference between the study groups was insignificant. It is concluded that dexamethasone is more effective in preventing postoperative nausea and vomiting after laparoscopic cholecystectomy than ondansetron. This is mainly determined by a significant reduction in the incidence of postoperative nausea.
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Anesteziol Reanimatol · Mar 2007
Randomized Controlled Trial[Use of vasopressin to correct hemodynamic disorders in patients with abdominal sepsis].
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Anesteziol Reanimatol · Jul 2006
Randomized Controlled Trial Comparative Study[Multi-injection thoracic paravertebral anesthesia during breast cancer operations].
Radical and/or reconstructive operations on the breast are a common surgical procedure. Despite treatment advances, this surgical intervention is frequently associated with postoperative pain, nausea, vomiting. When used during breast cancer operations, multi-injection thoracic paravertebral anesthesia (TPVA) has the potential that is necessary for the long-term preventive treatment of pain with fewer numbers of complications. ⋯ According to the type of anesthesia, the patients were randomly divided into 2 groups with 90 persons in each: (1) those undergoing TPVA with intravenous sedation; (2) those who were given the traditional multicomponent general anesthesia. Postoperative pain was much less in the TPVA group following 1, 3, 6, and 24 hours (p < 0.01) at rest and in motion. There is evidence suggesting that it is just the procedure that may become a main alternative to the traditional general anesthesia in a clinic that has sufficient experience with regional anesthesia and appropriate equipment, with minimum complications and a qualitatively better period of recovery.
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Anesteziol Reanimatol · Mar 2006
Randomized Controlled Trial[Effect of anesthesia with xenon and nitrous oxide with fentanyl on dynamics of cellular immunity and cytokines].
Immunological parameters were studied at randomization in 60 surgical patients during the similar operation--cholecystectomy made under combined endotracheal low-flow general anesthesia using N2O:O2+fentanyl in 32 patients and Xe:O2 in 28 patients. The time course of changes in cellular immunity and cytokines was closely related to the type of an anesthetic. ⋯ The differences in the action of the anesthetics were due to the fact that Xe had a greater narcotic potential, a protective action on neuroendocrine function, and no toxicity. Xe is indicated to patients with baseline immunodeficiency.
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Anesteziol Reanimatol · Mar 2006
Randomized Controlled Trial[Preoperative hypervolemic hemodilution with 6% hydroxyethyl starch 130/0,4 (HES 130/ 0.4) solution as a way of reducing needs for donor blood transfusion].
The efficacy of hypervolemic hemodilution (HHD) in reducing the rate of donor blood transfusion is controversely discussed. The present prospective, randomized, clinical study analyzes the impact of HHD with 6% hydroxyethyl starch (HES) 130/0.4 solution on the rate transfusion, laboratory parameters, and the incidence of complications as compared with those in the control group receiving no preoperative HHD. ⋯ Preoperative HHD in patients undergoing surgery with expected >30% blood loss leads to decreased needs for blood transfusion. The method is safe and easy-to-use.