The Lancet. Respiratory medicine
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Review Meta Analysis
Combination therapy versus monotherapy for pulmonary arterial hypertension: a meta-analysis.
Several randomised controlled studies and a previous meta-analysis have reported conflicting results regarding the effect of combined targeted therapy compared with monotherapy for pulmonary arterial hypertension (PAH). We did a systematic review and meta-analysis to assess the effects of a combination of PAH-specific therapies compared with monotherapy on predefined clinical worsening in PAH. ⋯ None.