World journal of gastroenterology : WJG
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World J. Gastroenterol. · Sep 2008
Direct hemoperfusion with a polymyxin B-immobilized cartridge in intestinal warm ischemia reperfusion.
To investigate the effectiveness of direct hemoperfusion with polymyxin B-immobilized fibers (DHP-PMX therapy) on warm ischemia-reperfusion (I/R) injury of the small intestine. ⋯ DHP-PMX therapy reduced warm I/R injury of the small intestine. IL-10 may play a role in inhibiting I/R injury during DHP-PMX therapy.
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World J. Gastroenterol. · Sep 2008
Case ReportsAtypical presentation of pioderma gangrenosum complicating ulcerative colitis: rapid disappearance with methylprednisolone.
Pioderma gangrenosum (PG) is an uncommon ulcerative cutaneous dermatosis associated with a variety of systemic diseases, including inflammatory bowel disease (IBD), arthritis, leukaemia, hepatitis, and primary biliary cirrhosis. Other cutaneous ulceration resembling PG had been described in literature. There has been neither laboratory finding nor histological feature diagnostic of PG, and diagnosis of PG is mainly made based on the exclusion criteria. ⋯ An atypical presentation of PG with UC was diagnosed. Pulse boluses of i.v. methyl-prednisolone were started, and after tapering steroids, complete resolution of the skin lesion was achieved in 3 wk. The unusual rapid healing of the skin ulceration with steroid mono-therapy and the atypical cutaneous presentation in this patient as well as the risk of misdiagnosis of PG in the clinical practice were discussed.
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World J. Gastroenterol. · Sep 2008
Review Meta AnalysisContinuous wound infusion of local anaesthetic agents following colorectal surgery: systematic review and meta-analysis.
To provide a specific review and meta-analysis of the available evidence for continuous wound infusion of local anaesthetic agents following midline laparotomy for major colorectal surgery. ⋯ The results of this systematic review and meta-analysis suggest that local anaesthetic wound infusion following laparotomy for major colorectal surgery is a promising technique but do not provide conclusive evidence of benefit. Further research is required including cost-effectiveness analysis.
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World J. Gastroenterol. · Sep 2008
Multicenter StudyHalothane hepatitis in Iran: a review of 59 cases.
To study halothane hepatitis (HH) in Iran and its associated risk factors. ⋯ HH remains an important cause of morbidity and mortality in centers still using this anesthetic. However, a large percentage of these cases could have been avoided. To lessen occurrence of further cases of HH, the authors suggest that in female patients having a history of surgery (or delivery) with general anesthesia, the use of halothane should be absolutely avoided. Utilization of proper substitutes in adults' anesthesia is advocated.