World journal of gastroenterology : WJG
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To evaluate the results of hepatic resection with ex-situ hypothermic perfusion and without veno-venous bypass. ⋯ Ex-situ liver resection and liver autotransplantation has shown a potential for treatment of complicated hepatic neoplasms that are unresectable by traditional procedures.
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World J. Gastroenterol. · Dec 2012
Meta AnalysisHighlights for α-fetoprotein in determining prognosis and treatment monitoring for hepatocellular carcinoma.
To explore the prognostic value in the monitoring of treatment efficacy of serial α-fetoprotein (AFP) in hepatocellular carcinoma (HCC) patients. ⋯ HCC patients presenting with an AFP response are at decreased risk of mortality. In addition, patients with an AFP response also present with a higher overall response rate and disease control rate.
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World J. Gastroenterol. · Dec 2012
Meta AnalysisEffectiveness of 5-flurouracil-based neoadjuvant chemotherapy in locally-advanced gastric/gastroesophageal cancer: a meta-analysis.
To investigate the effectiveness of 5-flurouracil-based neoadjuvant chemotherapy (NAC) for gastroesophageal and gastric cancer by meta-analysis. ⋯ Flurouracil-based NAC can safely improve overall survival rate of patients with gastroesophageal/gastric cancer. Additionally, NAC can down the tumor stage and improve R0 resection.
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World J. Gastroenterol. · Dec 2012
Electroacupuncture alleviates stress-induced visceral hypersensitivity through an opioid system in rats.
To investigate whether stress-induced visceral hypersensitivity could be alleviated by electroacupuncture (EA) and whether EA effect was mediated by endogenous opiates. ⋯ EA given at classical acupoint ST-36 alleviates stress-induced visceral pain, which is most likely mediated by opioid pathways in the periphery.
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World J. Gastroenterol. · Dec 2012
Oridonin induces apoptosis in gastric cancer through Apaf-1, cytochrome c and caspase-3 signaling pathway.
To investigate the effect and mechanism of oridonin on the gastric cancer cell line HGC-27 in vitro. ⋯ Apoptosis of HGC-27 induced by oridonin may be associated with differential expression of Apaf-1, caspase-3 and cytochrome c, which are highly dependent upon the mitochondrial pathway.