Postgraduate medicine
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Postgraduate medicine · Mar 2012
Randomized Controlled Trial Comparative StudyTolerability of concomitant use of selective serotonin reuptake inhibitors or serotonin-norepinephrine reuptake inhibitors and oxymorphone extended release.
Opioids and antidepressants are frequently prescribed for chronic low back pain (cLBP). This post hoc analysis was conducted to assess the tolerability of oxymorphone extended release (ER) for cLBP in patients taking selective serotonin reuptake inhibitors (SSRIs) or serotonin-norepinephrine reuptake inhibitors (SNRIs) compared with patients not taking SSRIs/SNRIs. ⋯ The concomitant use of oxymorphone ER with SSRIs or SNRIs was well tolerated in patients with cLBP.