Postgraduate medicine
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Postgraduate medicine · Mar 2023
Circulating platelets supply ST6Gal-1 in patients with IgA Nephropathy.
Our previous study showed ST6 β-galactoside α2,6-sialyltransferase 1 (ST6Gal-1) levels in plasma were associated with a slower progression of IgA nephropathy (IgAN). Platelets are the crucial regulator of cell surface glycosylation events in circulation by supplying glycosyltransferases. ⋯ In conclusion, human circulating platelets contain ST6Gal-1, which may be released by the activation of platelets in IgAN.
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Postgraduate medicine · Mar 2023
Psychometric properties of the Clarke questionnaire for hypoglycemia awareness in the Spanish population with type 2 diabetes.
The Clarke questionnaire, validated in Spanish language, assesses hypoglycemia awareness in patients with type 1 diabetes. This study aimed to analyze its psychometric properties in patients with type 2 diabetes (T2DM). ⋯ The Spanish version of the Clarke questionnaire was not valid or reliable for assessing hypoglycemia awareness in people with T2DM in Spanish population.
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Postgraduate medicine · Mar 2023
ReviewImpact of diet on sensory processing in early childhood: summary of an interactive webconference / expert roundtable discussion.
Pediatric feeding disorders can be seen in up to 45% of normally developing children aged under 5 years old, mainly during the first three years of life when the child has inadequate food intake and/or difficulty maintaining adequate growth, and/or lack of age-appropriate eating habit. This article describes the opinion of a group of experts on children eating patterns and how to manage pediatric feeding disorders, with the aim to improve the quality of life of children and their caregivers.
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Postgraduate medicine · Mar 2023
Review Meta AnalysisLow serum 25-hydroxyvitamin D levels are associated with increased cardiovascular morbidity and mortality.
There is controversy about the association between vitamin D and cardiovascular disease (CVD). This article aims to explore the association of serum 25-hydroxyvitaminD (25 OHD) with the risk of CVD. ⋯ The underlying mechanism still needs to be explored further, and well-designed RCTs are needed to confirm the role of vitamin D in the occurrence and development of CVD.
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Postgraduate medicine · Mar 2023
Randomized Controlled TrialRisk factors and prediction models of lymph node metastasis in papillary thyroid carcinoma based on clinical and imaging characteristics.
Papillary thyroid carcinoma (PTC) commonly presents with lymph node metastasis, which may be associated with worsened prognosis. This study aimed to comprehensively evaluate the risk factors of lymph node metastasis in PTC based on preoperative clinical and imaging data and to construct a nomogram model to predict the risk of lymph node metastasis. ⋯ Our study showed that independent risk factors for lymph node metastasis in PTC were sex, age, enlarged lymph node present on imaging, nodule diameter, and color Doppler TI-RADS grade. The nomogram constructed based on these independent risk factors can better predict the risk of lymph node metastasis.