Postgraduate medicine
-
Postgraduate medicine · May 2024
ReviewThe interaction between insulin resistance and Alzheimer's disease: a review article.
Insulin serves multiple functions as a growth-promoting hormone in peripheral tissues. It manages glucose metabolism by promoting glucose uptake into cells and curbing the production of glucose in the liver. Beyond this, insulin fosters cell growth, drives differentiation, aids protein synthesis, and deters degradative processes like glycolysis, lipolysis, and proteolysis. ⋯ This review aimed to explore the potential shared metabolic traits between Alzheimer's disease (AD) and IR disorders. It delves into the relationship between AD and IR disorders, their overlapping genetic markers, and shared metabolic indicators. Additionally, it addresses existing therapeutic interventions targeting these intersecting pathways.
-
Postgraduate medicine · May 2024
Recognizing cardiac murmurs in childhood: a survey of physicians' approaches and knowledge levels.
This study aimed to assess physicians' approach to cardiac murmurs and their level of knowledge about this sign, which is a crucial finding in childhood cardiac anomalies. ⋯ The study highlights the significant impact of various factors such as gender, specialization, internship duration, experience, and theoretical knowledge on the ability to recognize and approach cardiac murmurs. These findings underscore the importance of incorporating these factors into medical education and development programs, especially those aimed at improving cardiac examination skills.
-
Over-testing andover-treatment are common in children with croup at pediatric emergencydepartments (PED). The objective of the study was to improve care for childrenwith croup. ⋯ With this QI intervention,decreases in the rate of administration of NE to mild croup cases, antibioticprescription, X-ray, laboratory blood and respiratory PCR panel tests in allcroup cases were achieved without an increase in revisits. However, unnecessaryNE, antibiotic, and X-ray rates are still high.
-
Postgraduate medicine · May 2024
Predictive value of the HALP score for pre-eclampsia with severe features.
Predictive tests are needed to ensure the development and subsequent follow-up of pre-eclampsia, which is responsible for significant rates of morbidity and mortality during pregnancy. This study aimed to evaluate the predictive value of the Hemoglobin, Albumin, Lymphocyte, and Platelet (HALP) score for the severity of preeclampsia. ⋯ We found a significant correlation between the HALP score and preeclampsia with severe features. The HALP score may be useful in predicting the severity of preeclampsia.
-
Postgraduate medicine · May 2024
Calcium deficiency is associated with malnutrition risk in patients with inflammatory bowel disease.
Patients with inflammatory bowel disease (IBD) often have the condition of malnutrition, which can be presented as sarcopenia, micronutrient deficiencies, etc. Trace elements (magnesium, calcium, iron, copper, zinc, plumbum and manganese) belonging to micronutrients, are greatly vital for the assessment of nutritional status in humans. Trace element deficiencies are also the main manifestation of malnutrition. Calcium (Ca) has been proved to play an important part in maintaining body homeostasis and regulating cellular function. However, there are still a lack of studies on the association between malnutrition and Ca deficiency in IBD. This research aimed to investigate the role of Ca for malnutrition in IBD patients. ⋯ In patients with IBD, Ca deficiency is an independent factor for high malnutrition risk.