Zhonghua wei zhong bing ji jiu yi xue
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Zhonghua Wei Zhong Bing Ji Jiu Yi Xue · Sep 2018
Randomized Controlled Trial[Effect of different crystalloids on internal environment in patients with septic shock receiving early fluid resuscitation: a prospective randomized controlled trial].
To compare the effect of 0.9% NaCl solution, Ringer solution, and acetate sodium potassium magnesium calcium glucose solution (ASPMCG solution) on internal environment in patients with septic shock receiving early fluid resuscitation. ⋯ Chinese Clinical Trial Registry, ChiCTR-IOR-16009176.
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Zhonghua Wei Zhong Bing Ji Jiu Yi Xue · Sep 2018
[Effect of Galectin-9/Tim-3 pathway on the polarization of M1/M2 subtype in murine macrophages induced by lipopolysaccharide].
To investigate the meaning and molecular mechanisms of Galectin-9/T-cell immunoglobulin mucin-3 (Tim-3) pathway on lipopolysaccharide (LPS) induced murine macrophage M1/M2 subtype polarization. ⋯ LPS regulates macrophage M1/M2 subtype polarization via Galectin-9/Tim-3 signaling pathway. Low-doses of LPS can limit the development of inflammation by accommodating the expression and secretion of Galectin-9 to polarize macrophages to M2. High-doses of LPS promotes the development of inflammation by down-regulating the expression and secretion of Galectin-9 to polarize macrophages to M1.
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Zhonghua Wei Zhong Bing Ji Jiu Yi Xue · Sep 2018
[Clinical application of full age spectrum formula based on serum creatinine in patients with chronic kidney disease].
To compare the estimated glomerular filtration rates (eGFR) by five formulas based on serum creatinine (SCr), and to explore the diagnostic efficacy of full age spectrum (FAS) equation based on SCr for renal insufficiency in patients with chronic kidney disease (CKD). ⋯ Chinese Clinical Trial Registry, ChiCTR1800017727.
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Zhonghua Wei Zhong Bing Ji Jiu Yi Xue · Sep 2018
[Effect of lung strain on breathing mechanics in dogs with acute respiratory distress syndrome].
To explore the effect of lung strain on breathing mechanics in dogs with acute respiratory distress syndrome (ARDS). ⋯ In animal ARDS models, the larger the lung strain, the higher the Pplat and lung stress during mechanical ventilation, VT originated for lung strain 2.0 and 2.5 may further reduce Cst in ARDS models, when lung strain over 1.5, Pplat and lung stress increased significantly, which exceeded the safe range of LPV (35 cmH2O and 25 cmH2O, respectively), and further aggravated ventilator induced lung injury (VILI).
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Zhonghua Wei Zhong Bing Ji Jiu Yi Xue · Sep 2018
Meta Analysis[Effectiveness of Xuebijing in treatment of multiple organ dysfunction syndrome: a Meta analysis].
To systematical evaluate the effect of Xuebijing injection in the treatment of multiple organ dysfunction syndrome (MODS). ⋯ Xuebijing injection may through its strong cytokines clearance, platelet increase and blood coagulation improvement to protect the organ function in patients with MODS, so as to reduce the mortality and improve the prognosis.