Zhonghua wei zhong bing ji jiu yi xue
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Zhonghua Wei Zhong Bing Ji Jiu Yi Xue · Aug 2014
[The clinical application of pulse indicator continuous cardiac output monitoring in early fluid resuscitation for patients with severe acute pancreatitis].
To evaluate the therapeutic effect of early fluid resuscitation under the guidance of pulse indicator continuous cardiac output (PiCCO) on patients with severe acute pancreatitis (SAP). ⋯ The PiCCO device may be a useful adjunct for fluid resuscitation monitoring in patients with SAP within 72 hours. Early fluid resuscitation under the guidance of PiCCO may be helpful in improving tissue perfusion, reducing the application of blood purification, as well as shortening length of ICU stay. This program did not increase the risk of invasive mechanical ventilation, and no obvious change in mortality rate was observed.
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Zhonghua Wei Zhong Bing Ji Jiu Yi Xue · Aug 2014
[Effect of unilateral lung recruitment maneuver on hemodynamics and dead space ratio in pigs with unilateral acute respiratory distress syndrome].
To compare unilateral lung and traditional lung recruitment maneuver (RM) in animals with unilateral acute respiratory distress syndrome (ARDS) by implementing independent lung ventilation, and to explore the rational mechanical ventilation strategy for unilateral lung lesions. ⋯ For severe ARDS caused by single lung injury, implementation of independent lung RM on the basis of independent lung mechanical ventilation for individual lung was significantly superior to the traditional lung RM for the improvement of hemodynamic parameters and VD/VT.
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Zhonghua Wei Zhong Bing Ji Jiu Yi Xue · Aug 2014
[Effects of hypertonic sodium chloride hydroxyethyl starch solution on cerebral vasospasm following subarachnoid hemorrhage and its mechanism].
To investigate the protective effect and potential mechanisms of hypertonic sodium chloride hydroxyethyl starch solution (HSH) against the cerebral vasospasm (CVS) following subarachnoid hemorrhage (SAH). ⋯ The current results demonstrate that HSH attenuates the SAH-induced CVS, alleviates thickness of vessel wall, and increases lumen area via inhibition of VSMCs apoptosis.
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Zhonghua Wei Zhong Bing Ji Jiu Yi Xue · Aug 2014
[The protective effect of valproic acid on myocardium in rats with lethal scald injury and its mechanism].
To investigate the protective effects of valproic acid (VPA) on myocardium in rats following lethal burn injury and its mechanism. ⋯ VPA can attenuate cardiac injury and improve survival in a rodent model of lethal burn injury. These protective effects may be due to its inhibitory effects on histone deacetylase and caspase-3 activation.