Zhonghua wei zhong bing ji jiu yi xue
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Zhonghua Wei Zhong Bing Ji Jiu Yi Xue · Jun 2014
[The role of Nrf2 in the hydrogen treatment for intestinal injury caused by severe sepsis].
To investigate the role of Nrf2 on hydrogen treatment for intestinal injury caused by severe sepsis. ⋯ Through activation of Nrf2-antioxidant response element (ARE) pathway, hydrogen may increase the level of Nrf2, which is a kind of protective protein, in the intestine of mice, thus decreases the level of late pro-inflammatory factor, HMGB1, and it may protect the intestinal tissues in septic mice and increase the survival rate significantly.
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Zhonghua Wei Zhong Bing Ji Jiu Yi Xue · Jun 2014
[Reproduction of acute lung injury model induced by paraquat in piglet].
To reproduce acute lung injury (ALI) model induced by paraquat (PQ) in piglet. ⋯ By intraperitoneal injections of 20% PQ 20 mL, a stable PQ-induced ALI model can be reproduced in piglets.
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Zhonghua Wei Zhong Bing Ji Jiu Yi Xue · Jun 2014
Observational Study[Correlation of intestinal fatty acid binding protein and intestinal injury in severe sepsis].
To investigate the content of intestinal fatty acid binding protein (IFABP) and its clinical significance in patients with severe sepsis. ⋯ IFABP concentrations in patients with severe sepsis were significantly increased, and it is correlated well to IL-6, TNF-α and APACHEII score, but did not related obviously with AGI grade and the prognosis of the patients.
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Zhonghua Wei Zhong Bing Ji Jiu Yi Xue · Jun 2014
[An analysis of relevant factors of early death in acute paraquat poisoning].
To determine the clinical indicators of early death (within 72 hours) in patients with acute paraquat poisoning. ⋯ Paraquat concentrations in urine, WBC, Lac, poison dose and PaCO2 were the risk factors of the early death of the acute paraquat poisoning. The research suggests that paraquat concentration in urine, WBC and Lac are valuable in predicting early death of the patients.
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Zhonghua Wei Zhong Bing Ji Jiu Yi Xue · Jun 2014
Review Meta Analysis[Erythromycin for improving enteral nutrition tolerance in adult critical patients: a systematic review and meta-analysis].
To systematically review the efficacy and safety of erythromycin on enteral nutrition (EN) tolerance in adult critical care patients. ⋯ Postpyloric EN tube placement rate can be improved by erythromycin, which could be a choice of substitute for bedside intubation without fluoroscopy or endoscopic assistance. Based on the evidence, we recommended that intravenous erythromycin in a small dose of approximately 3 mg/kg weight as an option for EN intolerance in critical patients.