Zhonghua wei zhong bing ji jiu yi xue
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Zhonghua Wei Zhong Bing Ji Jiu Yi Xue · Nov 2013
[Experimental study of the effect of Shenmai injection on post-cardiac arrest syndrome in rabbit].
To observe the effects of Shenmai injection on post-cardiac arrest syndrome (PCAS) in rabbit and to discuss the underlying mechanism. ⋯ Severity of injury of different organs in rabbit cardiac arrest model showed positive correlation with the alterations in serum TNF-α, IL-1β, IL-6, NF-ΚB after cardiopulmonary resuscitation. Early use of Shenmai injection after cardiopulmonary resuscitation can retard the development of PCAS, especially in the protection of ischemia and hypoxia of myocardium after cardiopulmonary resuscitation.
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Zhonghua Wei Zhong Bing Ji Jiu Yi Xue · Oct 2013
Randomized Controlled Trial Comparative Study[Comparison of the effect of fluid resuscitation as guided either by lactate clearance rate or by central venous oxygen saturation in patients with sepsis].
To compare the efficacy of fluid resuscitation as guided by lactate clearance rate (LCR) and central venous oxygen saturation (ScvO2) in patients with sepsis. ⋯ Both LCR and ScvO2 can be taken as the index in confirming the endpoint of fluid resuscitation for patients with severe sepsis and septic shock. Fluid resuscitation therapy under the guidance of LCR is accurate and reliable in patients with severe sepsis and septic shock.
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Zhonghua Wei Zhong Bing Ji Jiu Yi Xue · Oct 2013
Randomized Controlled Trial[Effects of probiotics on blood glucose levels and clinical outcomes in patients with severe craniocerebral trauma].
To investigate the effects of probiotics on blood glucose levels and clinical outcomes in patients suffering from severe craniocerebral trauma. ⋯ Probiotics could facilitate blood glucose control in patients with severe craniocerebral injury. The underlying mechanisms and its long-term efficacy in this category of patients, however, need to be further investigated.
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Zhonghua Wei Zhong Bing Ji Jiu Yi Xue · Oct 2013
[The study of pro-B-type natriuretic peptide in the evaluation of the cardiac function in patients with severe sepsis].
To evaluate plasma N-terminal pro-B-type natriuretic peptide (NT-proBNP) levels as a marker of cardiac function during severe sepsis and septic shock. ⋯ Plasma NT-proBNP levels on day 7 in ICU could reflect the left ventricular systolic dysfunction in patients with severe sepsis and septic shock.
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Zhonghua Wei Zhong Bing Ji Jiu Yi Xue · Oct 2013
Comparative Study[Assessment of the value of acute physiology and chronic health evaluation II/IV prognostic models in elderly patients with sepsis].
To assess and compare the performance of acute physiology and chronic health evaluation II/IV (APACHEII/IV) prognostic models in elderly patients with sepsis. ⋯ The accuracy of APACHEII/IV are not ideal in foretelling mortality rate. Hospital mortality was underestimated with APACHEII in high risk patients, and it was underestimated with APACHEIV both in low and high risk patients, and it is even more prone to be underestimated in low risk group of APACHEIV. More accurate prognostic modality is in need in elderly patients with sepsis.