Zhonghua wei zhong bing ji jiu yi xue
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Zhonghua Wei Zhong Bing Ji Jiu Yi Xue · May 2013
[Protection of anisodamine on the mitochondrial injury induced by oxidative stress in swine with cardiac arrest].
To investigate the protection of anisodamine on cardiac ischemia/reperfusion (I/R) injury by oxidative stress by observing the changes in oxidation and antioxidant markers in plasma and myocardium, and the damage of cardiac mitochondria structure in pigs with cardiac arrest (CA). ⋯ Through regulating oxygen radical metabolism, anisodamine alleviates the injury to myocardial mitochondria structure and function injury as induced by oxidative stress.
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Zhonghua Wei Zhong Bing Ji Jiu Yi Xue · Apr 2013
Randomized Controlled Trial[The effect of ulinastatin on disbalance of inflammation and immune status in patients with severe sepsis].
To investigate the effect of ulinastatin (UTI) on the levels of immune regulatory cells,pro-inflammatory mediators, and the expression of human leukocyte antigen-DR (HLA-DR) in CD14⁺ monocytes. ⋯ UTI can decrease in the expression of Treg and Th17, inverse the ratio of Treg/Th17, decrease in the expression of IL-17, IL-6 and IL-10, ameliorate the immune status, and improve the expression of HLA-DR. UTI is expected to improve the prognosis of patients with severe sepsis.
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Zhonghua Wei Zhong Bing Ji Jiu Yi Xue · Apr 2013
Controlled Clinical Trial[Clinical research of timing of application of antibiotics in septic shock of pediatric patients].
To investigate the value of timing of antibiotics in pediatric septic shock. ⋯ With the early empirical anti-infection treatment in pediatric septic shocked patients, time for recovery from shock can be shortened and successful rate of resuscitation can be improved.
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Zhonghua Wei Zhong Bing Ji Jiu Yi Xue · Apr 2013
[Clinical study of prognostic value of interleukin-6 in severe acute pancreatitis].
To investigate the value of serum interleukin-6 (IL-6) level as a prognostic indicator in severe acute pancreatitis (SAP) patients. ⋯ IL-6 can be a useful indicator of the prognosis in the initial stage of SAP (48 hours).