Zhonghua wei zhong bing ji jiu yi xue
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Zhonghua Wei Zhong Bing Ji Jiu Yi Xue · May 2013
[Protection of anisodamine on the mitochondrial injury induced by oxidative stress in swine with cardiac arrest].
To investigate the protection of anisodamine on cardiac ischemia/reperfusion (I/R) injury by oxidative stress by observing the changes in oxidation and antioxidant markers in plasma and myocardium, and the damage of cardiac mitochondria structure in pigs with cardiac arrest (CA). ⋯ Through regulating oxygen radical metabolism, anisodamine alleviates the injury to myocardial mitochondria structure and function injury as induced by oxidative stress.
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Zhonghua Wei Zhong Bing Ji Jiu Yi Xue · Apr 2013
Randomized Controlled Trial[The effect of ulinastatin on disbalance of inflammation and immune status in patients with severe sepsis].
To investigate the effect of ulinastatin (UTI) on the levels of immune regulatory cells,pro-inflammatory mediators, and the expression of human leukocyte antigen-DR (HLA-DR) in CD14⁺ monocytes. ⋯ UTI can decrease in the expression of Treg and Th17, inverse the ratio of Treg/Th17, decrease in the expression of IL-17, IL-6 and IL-10, ameliorate the immune status, and improve the expression of HLA-DR. UTI is expected to improve the prognosis of patients with severe sepsis.
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Zhonghua Wei Zhong Bing Ji Jiu Yi Xue · Apr 2013
[Prognostic value of arterial lactate content combined with base excess in patients with sepsis: a retrospective study].
To study the prognostic value of arterial lactate combined with base excess (BE) in sepsis patients. ⋯ Combination of arterial lactate and BE can be a better indicator of prognosis in sepsis patients.