Zhonghua wei zhong bing ji jiu yi xue
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Zhonghua Wei Zhong Bing Ji Jiu Yi Xue · Jan 2016
Review Meta Analysis[The progress of light sedation for critically ill adult patients in intensive care unit].
The latest advance of sedation for critically ill adult patients in intensive care unit (ICU) was reviewed in order to provide certain clinical information for the ICU physicians about sedation. Guidelines, clinical research, Meta-analysis, and reviews in recent years were collected using electronic data base. Discussions included: (1) the definition of light sedation, and its effects on clinical outcome, stress, sleep and delirium; (2) light sedation strategies included: the target population, the target sedation strategy and daily sedation interruption, clinical assessment and monitoring of sedation, selection of sedative drugs, light sedation extenuation; (3) light sedation strategies and pain, agitation, delirium control bundles; (4) the problems and prospects of light sedation. ⋯ Routine use of benzodiazepines should be avoided, especially in patients with or at a risk of delirium. Prevention and treatment of agitation with a combination of non-pharmacologic or pharmacologic methods; ICU specification rules for pain, agitation and delirium prevention and treatment should be made. Light sedation is the main ICU sedation strategy in adult patients now, but must be individualized for each patient.
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Zhonghua Wei Zhong Bing Ji Jiu Yi Xue · Mar 2015
Meta Analysis[The efficacy of hypertonic saline treatment in cardiopulmonary resuscitation in animal model with cardiac arrest: a Meta-analysis].
To evaluate the efficacy of hypertonic saline (HS) treatment in cardiopulmonary resuscitation (CPR) in animal models of cardiac arrest (CA). ⋯ This systematic review indicates that HS infusion is followed by an improved ROSC rate, serum sodium concentration during CPR, and MAP at 90 minutes after ROSC in animal models of CA.
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Zhonghua Wei Zhong Bing Ji Jiu Yi Xue · Jun 2014
Review Meta Analysis[Erythromycin for improving enteral nutrition tolerance in adult critical patients: a systematic review and meta-analysis].
To systematically review the efficacy and safety of erythromycin on enteral nutrition (EN) tolerance in adult critical care patients. ⋯ Postpyloric EN tube placement rate can be improved by erythromycin, which could be a choice of substitute for bedside intubation without fluoroscopy or endoscopic assistance. Based on the evidence, we recommended that intravenous erythromycin in a small dose of approximately 3 mg/kg weight as an option for EN intolerance in critical patients.