Läkartidningen
-
Postoperative nausea and vomiting (PONV) continues to be a clinical problem with an unacceptably high incidence. Several studies have been performed that compare different antiemetics but thus far no successful monotherapy has been found. ⋯ In patients at great risk it is meaningful to recommend prophylactic antiemetics with a 2- or even 3-drug regimen, e.g. droperidol, ondansetron and dexamethasone. If the patients experience PONV despite treatment or prophylaxis, they should be treated with a drug from a group different from the one used earlier.