British journal of obstetrics and gynaecology
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Br J Obstet Gynaecol · Dec 1999
Randomized Controlled Trial Multicenter Study Comparative Study Clinical TrialA randomised controlled trial comparing transvaginal ultrasound, outpatient hysteroscopy and endometrial biopsy with inpatient hysteroscopy and curettage.
To compare the use of outpatient and inpatient procedures in the investigation of abnormal uterine bleeding. ⋯ Transvaginal sonography and endometrial biopsy can safely be used as the initial investigations in the management of abnormal uterine bleeding. Hysteroscopy can be used as a second line investigation. Outpatient hysteroscopy with local anaesthesia is well tolerated although general anesthesia may occasionally be necessary.
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Br J Obstet Gynaecol · Dec 1999
Randomized Controlled Trial Clinical TrialDoes an inflatable obstetric belt facilitate spontaneous vaginal delivery in nulliparae with epidural analgesia?
To assess whether an inflatable obstetric belt, synchronised to apply uniform fundal pressure during a uterine contraction, reduces operative delivery rates when used in the second stage of labour. ⋯ The inflatable obstetric belt did not significantly reduce operative delivery rates when used in this clinical setting in the second stage of labour.
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Br J Obstet Gynaecol · Nov 1999
Randomized Controlled Trial Comparative Study Clinical TrialIntramuscular opioids for maternal pain relief in labour: a randomised controlled trial comparing pethidine with diamorphine.
To compare the pain relief and side effects of intramuscular pethidine with intramuscular diamorphine in labour. ⋯ Intramuscular diamorphine in labour appears to have some benefits, compared with intramuscular pethidine, but the trial was small and further research, particularly into alternative opioids and long term effects on the infants is still needed.
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Br J Obstet Gynaecol · Oct 1999
Randomized Controlled Trial Clinical TrialMisoprostol compared with methylergometrine for the prevention of postpartum haemorrhage: a double-blind randomised trial.
To compare the efficacy and side effects of misoprostol, compared with methylergometrine, for the prevention of postpartum haemorrhage. ⋯ This study suggests that although protection from postpartum haemorrhage using parenteral methylergometrine and oral misoprostol is nearly equal, misoprostol is associated with more side effects.
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Br J Obstet Gynaecol · Sep 1999
Randomized Controlled Trial Clinical TrialTwo dosing regimens for preinduction cervical priming with intravaginal dinoprostone pessary: a randomised clinical trial.
To compare the efficacy within 24 hours of a three-times-a-day intensive dosing regimen with a standard once daily dosing regimen using dinoprostone vaginal pessary in preinduction cervical priming. ⋯ Preinduction cervical priming with the intensive dosing regimen improves the chances of successful ripening within 24 hours for primigravidae with unfavourable cervical scores at full term singleton pregnancies, and shortens the interval from priming to induction, and priming to delivery. This regimen may be more cost effective by shortening the period of hospital stay. The overall incidence of adverse reactions to the mother and fetus during priming was low. However, close fetal surveillance must be maintained, particularly in pregnancies complicated with oligohydramnios.