Romanian journal of internal medicine = Revue roumaine de médecine interne
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Comparative Study
Small intestinal bacterial overgrowth produces symptoms in irritable bowel syndrome which are improved by rifaximin. A pilot study.
Searching for the role of small intestinal bacterial overgrowth (SIBO) in the pathogenesis of mechanisms and symptoms in patients with irritable bowel syndrome (IBS). ⋯ Rifaximin effectively normalized the GHBT and reduced the IBS symptoms by possibly counteracting the SIBO. Whether such therapeutic approach is ultimately associated with symptom improvement in the long term, however, requires additional studies.
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Oxidative stress is the first step involved in mutagenesis, carcinogenesis and aging. There has been great interest in recent years in potentially health benefits of dietary and antioxidant supplements in cancer prevention. ⋯ This meta-analysis found no evidence in favor of a protective effect of the studied antioxidant supplements in the prevention of colorectal cancer or cancer related mortality. Only selenium supplementation might have anticarcinogenic effects and requires further research.