Zhongguo wei zhong bing ji jiu yi xue = Chinese critical care medicine = Zhongguo weizhongbing jijiuyixue
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Zhongguo Wei Zhong Bing Ji Jiu Yi Xue · Nov 2009
Randomized Controlled Trial[Effects of different doses of ulinastatin on inflammatory response and pulmonary function after cardiopulmonary bypass].
To evaluate the effect of ulinastatin (UTI) on the changes in inflammatory cytokines and inflammatory response as a result of cardiopulmonary bypass (CPB) in cardiac valvular replacement surgery and to investigate the protective effect of UTI on lungs. ⋯ During the CPB, UTI can significantly inhibit the inflammatory cytokine release and reduce the inflammatory response, lessen the lung inflammatory response to CPB and protect lung function, the effect of UTI shows a dose-effect relationship.
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Zhongguo Wei Zhong Bing Ji Jiu Yi Xue · Nov 2009
[Clinical investigation on the compliance and the validity of ventilator bundle].
To investigate the compliance of ventilator bundle implementation and its preventive effect on ventilator associated pneumonia (VAP). ⋯ The poor compliance of ventilator bundle is an important factor in impacting the efficacy of ventilator bundle.
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Zhongguo Wei Zhong Bing Ji Jiu Yi Xue · Nov 2009
[The role of expression of Toll-like receptor 2 and Toll-like receptor 4 in hyperoxia-induced acute lung injury in rat].
To investigate the role of Toll-like receptors (TLRs) in pathogenesis of hyperoxia- induced acute lung injury (ALI). ⋯ The prolonged exposure to hyperoxia may cause ALI in rat, and TLR2 and TLR4 plays an important role in the development of hyperoxia-induced ALI in rat.
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Zhongguo Wei Zhong Bing Ji Jiu Yi Xue · Nov 2009
[Experimental study of early blood purification in the treatment of post traumatic pulmonary fat embolism].
To study the effect of early continuous blood purification (CBP) in the treatment of post-traumatic pulmonary fat embolism in dog. ⋯ The therapy of CBP could decrease the level of the serum TNF-alpha, IL-1 beta , IL-6 and EVLW, MPAP, PCWP, which could ameliorate gas exchange and oxygenation of the lung. And it also could reduce the number of pulmonary fat emboli and decrease the incidence of pulmonary fat embolism caused by femoral intramedullary operation.