Zhongguo wei zhong bing ji jiu yi xue = Chinese critical care medicine = Zhongguo weizhongbing jijiuyixue
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Zhongguo Wei Zhong Bing Ji Jiu Yi Xue · Mar 2009
Randomized Controlled Trial[Clinical effects of ulinastatin and thymosin alpha1 on immune-modulation in septic patients].
To analyze clinical effect of immuno-modulatory therapy with ulinastatin and thymosin alpha1 on patients with sepsis. ⋯ The immuno-modulation therapy of ulinastatin and thymosin alpha1 can remarkably improve the duration of MV and the development rate of MODS and mortality rate on 28 days in the patients with sepsis, probably due to its effect in ameliorating the immuno-imbalance state of the patients. However, the duration of infection and length of ICU stay are not effected.
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Zhongguo Wei Zhong Bing Ji Jiu Yi Xue · Mar 2009
Randomized Controlled Trial[Effect of continuous blood purification and thymosin alpha1 on the cellular immunity in patients with severe sepsis: a prospective, randomized, controlled clinical trial].
To discuss the effect of continuous blood purification (CBP), thymosin alpha1 and combined therapy on cellular immunity in patients with severe sepsis. ⋯ CBP and thymosin alpha1 could increase cellular immunity in patients with severe sepsis, promote recovery of organ function and improve prognosis. The effect of CBP appears earlier and more pronounced. Combined treatment can be more effective.
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Zhongguo Wei Zhong Bing Ji Jiu Yi Xue · Mar 2009
Randomized Controlled Trial[A clinical study of the serum vascular endothelial growth factor in patients with severe sepsis].
To examine the dynamic changes in serum vascular endothelial growth factor (VEGF) levels in patients with severe sepsis, and to investigate its relationship with acute physiology and chronic health evaluation II (APACHE II) score and some clinical parameters of patients. ⋯ The VEGF levels are elevated at onset in severe sepsis patients. The VEGF levels lowered along with the course of the disease in survival group, but it lowers inconspicuously in death group. VEGF levels can reflect the severity of sepsis in certain degree.