Zhongguo wei zhong bing ji jiu yi xue = Chinese critical care medicine = Zhongguo weizhongbing jijiuyixue
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Zhongguo Wei Zhong Bing Ji Jiu Yi Xue · Dec 2009
[Study on apoptosis of splenic lymphocytes in rats with sepsis].
To observe the change in number of spleen T lymphocytes and B lymphocytes and apoptosis of splenocytes in rats with sepsis, and explore the mechanism of immune imbalance in sepsis. ⋯ Disturbance of immunological function exists in the rats with sepsis at 24 hours after CLP. The number of CD4(+) T lymphocyte, B lymphocyte was obviously reduced, apoptotic splenocytes were obviously increased. Bax and Bcl-2 play an important role in apoptosis of splenocytes in sepsis.
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Zhongguo Wei Zhong Bing Ji Jiu Yi Xue · Nov 2009
Randomized Controlled Trial[Effects of different doses of ulinastatin on inflammatory response and pulmonary function after cardiopulmonary bypass].
To evaluate the effect of ulinastatin (UTI) on the changes in inflammatory cytokines and inflammatory response as a result of cardiopulmonary bypass (CPB) in cardiac valvular replacement surgery and to investigate the protective effect of UTI on lungs. ⋯ During the CPB, UTI can significantly inhibit the inflammatory cytokine release and reduce the inflammatory response, lessen the lung inflammatory response to CPB and protect lung function, the effect of UTI shows a dose-effect relationship.
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Zhongguo Wei Zhong Bing Ji Jiu Yi Xue · Nov 2009
[Clinical investigation on the compliance and the validity of ventilator bundle].
To investigate the compliance of ventilator bundle implementation and its preventive effect on ventilator associated pneumonia (VAP). ⋯ The poor compliance of ventilator bundle is an important factor in impacting the efficacy of ventilator bundle.