Polskie Archiwum Medycyny Wewnętrznej
-
Pol. Arch. Med. Wewn. · Dec 2019
Blood pressure and cholesterol control in patients with hypertension and hypercholesterolemia: the results from the Polish multicenter national health survey WOBASZ II.
Persons with multiple risk factors of cardiovascular disease (CVD) are at a greater risk than persons exposed to a single risk factor. Control of specific risk factors of CVD in Poland is rather poor. Effective control of comorbid hypertension and hypercholesterolemia seems especially challenging. ⋯ Comorbid hypertension and hypercholesterolemia were observed in one‑third of the Polish population (included in WOBASZ II study). Only 5.4% have both risk factors controlled. After adjustment for covariates, female sex, nonsmoking, comorbid CVD or diabetes, the frequency of medical visits, and high level of education appeared to increase the proportion of controlled hypertension or hypercholesterolemia.
-
Pol. Arch. Med. Wewn. · Dec 2019
Meta AnalysisExaggerated systolic hypertensive response to exercise predicts cardiovascular events: a systematic review and meta-analysis.
The pathophysiology of exaggerated systolic hypertensive response to exercise (SHRE) is not fully understood, with contradictory data on its role in predicting cardiovascular (CV) events. ⋯ Our study supports the clinical relevance of exaggerated SHRE as a predictor of composite and individual CV clinical outcome. These findings should be considered as thought‑provoking evidence for better stratification and, consequently, for optimal management of this high‑risk population.
-
Pol. Arch. Med. Wewn. · Dec 2019
Observational StudyFluctuations in circulating endothelial progenitor cell levels and acute cardiac graft rejection.
Endothelial progenitor cells (EPCs) in nontransplant settings have reparative properties. However, their role in heart transplantation (HT) is not well defined. ⋯ Early reduction of EPC levels was related to a lower risk of ACR or AMR. Greater changes of EPC‑levels during follow‑up were associated with a significantly higher risk of rejection.
-
Pol. Arch. Med. Wewn. · Dec 2019
Comparative StudyCharacteristics of amino acid profiles and incretin hormones in patients with gallstone disease: a pilot study.
Gallstone disease is associated with insulin resistance, type 2 diabetes mellitus, and increased risk of incident ischemic heart disease. It is known that the profile of branched‑chain amino acids (BCAAs) is altered in cardiac diseases as well as metabolic diseases, such as diabetes and obesity. The role of BCAAs in gallstone disease is still not known. ⋯ The mean fasting and postprandial levels of valine, isoleucine, leucine, and lysine were higher in the study group than in controls (all P.