Polskie Archiwum Medycyny Wewnętrznej
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Pol. Arch. Med. Wewn. · Nov 2020
ReviewNonalcoholic fatty liver disease and the risk of metabolic comorbidities: how to manage in clinical practice.
Nonalcoholic fatty liver disease (NAFLD) is a clinical condition that encompasses various forms of liver damage not caused by chronic alcohol consumption. In the absence of other etiologies, it ranges from steatosis to nonalcoholic steatohepatitis and cirrhosis. The prevalence of NAFLD has considerably increased over the last years owing to the current lifestyle (unhealthy diet and sedentarism). ⋯ Nowadays, we are in a race to find the first drug able to stop the incidence of NAFLD and reverse the disease in patients at more advanced stages. Meanwhile, the management of the NAFLD metabolic overload, including weight loss, cardiovascular protection, insulin sensitization, and lipid reduction, is the only strategy to improve hepatic and extrahepatic outcomes. In this review, we aimed to describe the management of the main metabolic disorders related to NAFLD, such as type 2 diabetes, arterial hypertension, and dyslipidemia.
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Pol. Arch. Med. Wewn. · Nov 2020
Meta AnalysisAssessment of the risk of incident heart failure in osteoporosis patients: a systematic review and meta-analysis of eligible cohort studies.
A relation between cardiovascular diseases and bone health is increasingly reported. However, the association between osteoporosis and incident heart failure (HF) has not been yet determined. ⋯ Osteoporosis was associated with a modest but significantly increased risk of incident HF. Considering the limited number and quality of available studies, future high‑quality data are required to further demonstrate the association between osteoporosis and incident HF.