Polskie Archiwum Medycyny Wewnętrznej
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Pol. Arch. Med. Wewn. · Mar 2021
ReviewPost-treatment surveillance in colorectal cancer patients: how to do it? A comprehensive review.
Patients who undergo a potentially curative treatment of colorectal cancer are at risk of local recurrences, distant metastases, and metachronous neoplasms. Accordingly, these patients typically undergo a multimodal oncological surveillance aimed to detect relapses early, with an expectation of a higher rate of radical retreatments and better overall survival. ⋯ Typical surveillance recommended by guidelines includes regular physical examinations, computed tomography scans, serum carcinoembryonic antigen monitoring, and colonoscopy. The objective of this comprehensive review is to discuss different patterns of relapses observed in colorectal cancer patients, present diagnostic options, and summarize different strategies and recommendations of the posttreatment surveillance.
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Pol. Arch. Med. Wewn. · Mar 2021
Epicardial, pericardial fat and glucagon-like peptide-1 and 2 receptors expression in stable patients with multivessel coronary artery disease: an association with renin-angiotensin-aldosterone.
The expression of glucagon‑like peptide receptors (GLP‑Rs) in epicardial fat (EF) and pericardial fat (PF) depots might be involved in the pathogenesis of cardiovascular diseases. ⋯ In stable patients with MVD, the relative mRNA expression for both GLP receptors revealed significant associations with majority of analysed RAAS components.
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Pol. Arch. Med. Wewn. · Mar 2021
Inflammatory bowel disease is associated with higher seroprevalence rates of antibodies against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).
According to the current data, there has been no increase in the incidence of COVID‑19 in patients with inflammatory bowel disease (IBD). ⋯ Patients with IBD may be at higher risk of developing SARS‑CoV‑2 infection, defined as the presence of elevated levels of anti-SARS‑CoV‑2 IgG antibodies, but not of having a symptomatic and / or severe course of COVID‑19 compared with healthcare professionals without IBD.