Recenti progressi in medicina
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It is well known that heroin overdose may cause rhabdomyolysis. Sometimes a myocardial involvement complicates its course. ⋯ We think that heroin has a direct myotoxic effect on both myocardium and skeletal muscle. Yet we cannot exclude that hypoxia, acidosis, vasoconstrictive substances released by muscle necrosis, or hypersensitivity reactions associated with heroin or some of its adulterants are involved in myocardial injury.