Cardiologia (Rome, Italy)
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Cardiologia (Rome, Italy) · Oct 1998
Review Case Reports[Recurrent ventricular fibrillation in acute myocardial infarct treated successfully by coronary angioplasty: a clinical case in favor of the hypothesis of the arrhythmogenicity of the coronary thrombus?].
We describe a patient with acute myocardial infarction due to thrombotic occlusion of the left anterior descending coronary artery. Following thrombolytic therapy, five episodes of ventricular fibrillation recurred despite the absence of profibrillatory factors other than myocardial ischemia. ⋯ After successful mechanical artery recanalization, no recurrences of the malignant arrhythmia were observed. This case supports the concept, recently demonstrated in animals, that the process of intracoronary thrombosis itself may have arrhythmogenic effects above and beyond the impact of myocardial ischemia induced by coronary occlusion per se.