Radiology
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To compare serum creatinine (SCr) level- and estimated glomerular filtration rate (eGFR)-based screening methods for identifying adult inpatients at risk for contrast medium-induced nephrotoxicity (CIN). ⋯ Screening using eGFR <45 mL/min/1.73 m(2) instead of common SCr thresholds would significantly increase the number of inpatients identified to be at risk for CIN but would reduce misidentification of a large number of inpatients at low risk according to eGFR criteria.
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Controlled Clinical Trial
Split-bolus spectral multidetector CT of the pancreas: assessment of radiation dose and tumor conspicuity.
To assess tumor conspicuity and radiation dose with a new multidetector computed tomography (CT) protocol for pancreatic imaging that combines spectral CT and split-bolus injection. ⋯ Split-bolus spectral multidetector CT resulted in vascular, liver, and pancreatic attenuation and tumor conspicuity equal to or greater than that with multiphase CT, with a 43% reduction in radiation dose.
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Comparative Study
Axillary lymph node biopsy in newly diagnosed invasive breast cancer: comparative accuracy of fine-needle aspiration biopsy versus core-needle biopsy.
To compare the diagnostic accuracy of ultrasonographically (US)-guided fine-needle aspiration biopsy (FNAB) and core-needle biopsy (CNB) of the axillary lymph nodes (LNs) of patients with newly diagnosed invasive breast cancer. ⋯ When accurate preoperative staging of the axilla is needed in patients with newly diagnosed invasive breast cancer, CNB is more sensitive than FNAB.
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To develop and validate a mathematical radiation dose optimization model for computed tomography (CT) of the chest, abdomen, and pelvis. ⋯ CT image quality and radiation dose can be mathematically predicted and optimized on the basis of patient size and radiologist-specific image noise target curves.