Zhonghua yi xue za zhi
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Zhonghua yi xue za zhi · Apr 2008
Multicenter Study Clinical Trial[Application of remifentanil in neurosurgical anesthesia: a multi-center study].
To observe the hemodynamic changes, recovery profiles, and side effects of propofol and remifentanil anesthesia by target controlled infusion (TCI). At different neurosurgical stages in patients undergoing neurosurgical operations. ⋯ When combined with 3 microg/ml propofol, the plasma target-concentrations of remifentanil, 3.0, 3.5, 3.6, and 3.4 ng/ml before skin incision, during skull opening, during intracranial procedure, and at skull closing respectively, can provide rapid induction, faster emergence , and better hemodynamic stability.