Przegla̧d lekarski
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Repolarization disorders leading to ventricular tachyarrhythmias are common causes of sudden cardiac death. Two of the disorders have been recently described at the molecular level revealing gene mutations: long QT syndrome, characterized by a prolonged QT interval corrected for heart rate and high incidence of malignant ventricular tachycardia, mainly torsade de pointes, and Brugada syndrome characterized by a ST segment elevation in the right precordial leads (V1-V3), right bundle branch block and idiopathic ventricular fibrillation. ⋯ On the basis of these repolarization disorders lay ion channel dysfunctions. The new discoveries may in the future allow a better diagnosis by genetic testing and raise the possibility of effective treatment by means of the gene-specific therapy.
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Cerebral vasospasm is a complication diagnosed in angiography among about 2/3 of patients after subarachnoid haemorrhage with ruptured cerebral aneurysm. In half of the cases it appears in disturbances of consciousness, neurological deficits and vegetative disturbances. It's final result can be ischemic stroke. ⋯ Undertaking hemodynamic treatment; 4. Aminosteroid administration; 5. Performance of angioplasty in the case of lack of reaction to previous types of treatment of cerebral vasospasm.