Revista brasileira de anestesiologia
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Rev Bras Anestesiol · Mar 2012
Randomized Controlled TrialAssessment of induction, recovery, agitation upon awakening, and consumption with the use of two brands of sevoflurane for ambulatory anesthesia.
Due to its pharmacological characteristics, sevoflurane is the ideal anesthetic for short-duration procedures. There are two brands of sevoflurane in the Brazilian market, Sevocris® and Sevorane®, with different formulations and packaging. The objective of this study was to assess whether there are differences between the two anesthetics regarding induction, maintenance, recovery, and consumption. ⋯ There was no difference between groups regarding the duration of the procedure, the anesthesia, and the parameters evaluated at induction. In Group 1, the number of children who required additional bolus of sevoflurane for anesthesia maintenance was higher than in Group 2 (p<0.05). The fraction of inspired and expired sevoflurane at the end of the procedure was lower in Group 1 (p<0.001). Upon awakening, BIS value was lower in Group 1 (p=0.045). Other parameters evaluated in recovery showed no difference between groups. The use of anesthesia was similar between groups.
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Rev Bras Anestesiol · Mar 2012
Randomized Controlled Trial Comparative StudyCigarette smoking and the effect of dexmedetomidine and fentanyl on tracheal intubation.
To compare the effect of dexmedetomidine and fentanyl on hemodynamic changes in chronic male smokers. ⋯ Dexmedetomidine, which was applied via infusion at a loading dose of 1μg.kg(-1) 10 minutes before anesthesia induction in chronic male smokers, better suppressed increases in heart rate and rate-pressure product at 1 and 3 minutes after intubation compared to the group receiving 3μg.kg(-1) fentanyl.