Biulleten' eksperimental'noĭ biologii i meditsiny
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Biull Eksp Biol Med · Feb 1991
[The effect of heparin and thromboplastin on the half-life of 125I-protein C in the blood flow of rats].
The influence of heparin and thromboplastin on the halflife of 125I-protein C in rat blood was under investigation. It was found that t1/2 of protein C was of 2.3 h. ⋯ Upon the 40-min infusion of thromboplastin the rate of 125I-protein C decay in blood enhanced. That could be explained by the generation of the endogenous thrombin and participation of thrombomodulin in the protein C activation as well as in the removal of the endogenous thrombin from blood.