Revista Brasileira de terapia intensiva
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Rev Bras Ter Intensiva · Oct 2014
Review Meta AnalysisHemodynamic optimization in severe trauma: a systematic review and meta-analysis.
Severe trauma can be associated with significant hemorrhagic shock and impaired organ perfusion. We hypothesized that goal-directed therapy would confer morbidity and mortality benefits in major trauma. ⋯ Following severe trauma, early goal-directed therapy was associated with lower mortality and shorter durations of intensive care unit and hospital stays. The findings of this analysis should be interpreted with caution due to the presence of significant heterogeneity and the small number of the