Alternative therapies in health and medicine
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Altern Ther Health Med · Mar 2000
Randomized Controlled Trial Clinical TrialRandomized prospective double-blind placebo-controlled study of dextrose prolotherapy for knee osteoarthritis with or without ACL laxity.
Use of prolotherapy (injection of growth factors or growth factor stimulators). ⋯ Prolotherapy injection with 10% dextrose resulted in clinically and statistically significant improvements in knee osteoarthritis. Preliminary blinded radiographic readings (1-year films, with 3-year total follow-up period planned) demonstrated improvement in several measures of osteoarthritis severity. ACL laxity, when present in these osteoarthritic patients, improved.