The lancet. Diabetes & endocrinology
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Lancet Diabetes Endocrinol · Dec 2015
Randomized Controlled Trial Multicenter StudyMyostatin antibody (LY2495655) in older weak fallers: a proof-of-concept, randomised, phase 2 trial.
Myostatin inhibits skeletal muscle growth. The humanised monoclonal antibody LY2495655 (LY) binds and neutralises myostatin. We aimed to test whether LY increases appendicular lean body mass (aLBM) and improves physical performance in older individuals who have had recent falls and low muscle strength and power. ⋯ Eli Lilly and Company.