Journal of diabetes science and technology
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J Diabetes Sci Technol · Nov 2011
Meta AnalysisMeta-analysis of overnight closed-loop randomized studies in children and adults with type 1 diabetes: the Cambridge cohort.
We reviewed the safety and efficacy of overnight closed-loop insulin delivery compared with conventional continuous subcutaneous insulin infusion (CSII) in two distinct age groups with type 1 diabetes mellitus (T1DM), young people aged 5 to 18 years and adults, combining data of previously published randomized studies. ⋯ Overnight closed loop may improve glycemic control and reduce nocturnal hypoglycemia in both young people and adults with T1DM.